Celiac disease (CeD) is a long-term inflammatory disorder of the small intestine triggered by the ingestion of gluten in genetically susceptible individuals. When gluten is consumed, it leads to damage to the intestinal lining, resulting in poor absorption of nutrients. Nutrient malabsorption is a significant risk factor for numerous problems associated with CeD. Still, it is also influenced by genetic, immunological, and environmental variables, and it has a key role in human well-being. The clinical presentation of CeD can vary widely, ranging from no symptoms to severe symptoms, reflecting its impact on multiple organ systems. Currently, the only evidence-based treatment is a gluten-free diet (GFD), which can fully repair intestinal damage and stop disease progression. If left undiagnosed, CeD can lead to severe complications in both children and adults. The present study involved 40 patients with type 1 diabetes (DMT1) and 40 patients with celiac disease (CD). The patients were classified into treated and untreated groups, which were subsequently compared to 40 control individuals. The ROC curve analysis of PERP results indicated that the cut-off value for patients with treated gluten was 3.46, surpassing the cut-off value of 2.62 for patients with untreated gluten. The anti-tTga ROC curve showed a cut-off value 9.15 for individuals with treated gluten, which is lower than the cutoff value 14.87 for those with untreated gluten. In patients with type 1 diabetes mellitus with untreated gluten sensitivity, the results indicated a significantly elevated Ttg-IgA level, with a p-value of 0.02, in comparison to healthy individuals. The PERP level exhibited a markedly elevated p-value (?0.0001) for patients with type 1 diabetes mellitus and untreated gluten compared to healthy individuals. The findings indicated that PERP and Anti-tTga may be essential in recognizing gluten intolerance as a risk factor for type 1 diabetes. Additionally, the study assessed additional variables such as glutamic pyruvic transaminase, hemoglobin A1c (HbA1c), fasting blood sugar (FBS), Glutamic Pyruvic Transaminase (GPT), Complete Blood Count (CBC), Glutamic Oxaloacetic Transaminase (GOT), and Hemoglobin (HBG)
a las Tecnologías de la Información y las Comunicaciones (TIC) y aquellas personas que no han tenido dicha oportunidad, al igual que la diferencia en el nivel de uso para diferentes actividades. Con el propósito de reducir esta brecha, se emprenden procesos en el marco del fenómeno denominado inclusión digital. Estos fenómenos, a pesar de ser resientes en el campo teórico, poseen diversos acercamientos, lo cual es una dificultad para los investigadores al momento de iniciar a construir el respectivo marco teórico o revisión conceptual. En el presente documento se realiza una clasificación de literatura de la perspectiva social de la brecha digital y la inclusión digital con base en un proceso de revisión sistemática de literatura.\nComo conclusión se puede mencionar que contar con una clasificación de material bibliográfico sobre los fenómenos, permite a los investigadores agilizar sus procesos e iniciar sus investigaciones con un mayor enfoque y con fuentes de primera mano.
Purpose: In this study, we investigated the effects of three agents frequently used in daily life for medical expulsive therapy on each other.\nMaterials and methods: A total of 143 patients meeting the criteria were included in the study. Patients were divided into three homogeneous drug groups which were tamsulosin group (n:48), alfuzosin group (n:47) and silodosin group (n:48). The time of stone expulsion, analgesic needs, side effects of the medicine and endoscopic intervention needs of the patients were recorded.\nResults: The rate of stone expulsion was 70.8% (n:34) in tamsulosin group, 70.2% (n:33) in alfuzosin group, and 75% (n:36) in silodosin group. No significant difference was observed among the rates of stone expulsion in three groups, and the rates of stone expulsion were similar (p=0.778). The duration of stone expulsion has significant differences in the groups (p=0.012). the time of stone expulsion in tamsulosin was 2.33±0.78 days longer than the one in Silodosin, indicating a significant difference. There was no significant difference between tamsulosin-alfuzosin and silodosin-alfuzosin (respectively p=0.147, p=0.925).\nConclusions: The results of this study showed that medical expulsive therapy by using alpha blocker agents are safe and efficacious. This option must be kept in mind who are not volunteer for surgery as the first-step treatment for eligible patients.
The article examines the main areas of cooperation between the Orthodox Church and medical institutions in Russia. It is shown that the Church, as well as medical and preventive institutions, are trying to determine the necessary and appropriate vectors for the development of medical care for people who need it. The article reveals historical parallels, indicating the readiness of doctors and representatives of the Orthodox Church to solve emerging problems and determine the prospects for development. The relationship between the spiritual and physical health of the Russian population is shown, which manifests itself in the context of socio-economic reforms.\nWe consider the historical experience of organization of church medical aid, which can help in the development of algorithms and conceptual principles for the creation of charitable communities, the formation of which will ensure the stable functioning of medical institutions, regardless of political situation and geographical location.\nThe author independently conducted an analytical review of domestic and foreign literature on this topic, compiled a research program, developed statistical accounting forms, collected medical, historical and statistical information. The planning, compilation of statistical processing programs and the processing itself were carried out in educational institutions and scientific centers.
Individuals at project level are becoming more responsible and accountable for the job they perform. Due to increase in complexity of project requirements, there is considerable influence on the responsibilities and roles of project professionals of software industry. The present study aims to examine the relationship and impact of structural and psychological empowerment on job performance of project professionals in software development industry. Data is collected from 219 employees working on projects in 60 software companies of Punjab that are registered with Pakistan Software Houses Association. The results of correlation and multiple regression analysis, reveal that both structural and psychological empowerment have significantly positive effect on the performance of project professionals. The findings suggest that both types of empowerment play major role in influencing employees’ job performance of software industry to enhance success in projects.
By an ordered semihypergroup, we mean a semihypergroup equipped with a partial order relation. An ordered semihypergroup is a natural generalization of a semigroup with a hyper operations and a partial order. In this paper, we try to obtain a more general form of a fuzzy left (right) hyperideal and a fuzzy interior hyperideal in an ordered semihypergroup. The concepts of an -fuzzy left (right) hyperideal and an -fuzzy interior hyperideal are introduced and several related properties are investigated. We show that in regular and intra-regular ordered semihypergroups the concepts of (alpha, beeta)-fuzzy hyperideal and (alpha, beeta)-fuzzy interior hyperideal coincide. In the last of this paper, the characterizations of simple ordered semihyper-groups are obtained and several related theorems are discussed.
In this survey paper, we characterize the reinforcement learning for mobile robot navigation and state the importance of artificial intelligence in achieving machine learning techniques. We review various reinforcement learning approaches that have been proposed for mobile robot navigation classifying them under the learning paradigms. Reinforcement learning (RL) is presented as an autonomous learning procedure that is suitable for unknown environments. We describe some challenging learning policies of RL approach that arise in path planning of mobile robot navigation, in particular in Markovian environments, and present their possible solution methods. Finally, we present future scope and show suitable machine learning approaches for learning in mobile robot path planning.
A partir de la formulación del concepto de sustentabilidad, surge la necesidad de considerar en forma integral y global los procesos productivos y de alcanzar medidas de la sustentabilidad. De este modo se construyeron listas de indicadores y características que debían tener los mismos. Luego se propusieron conceptos, criterios y metodologías para seleccionar/desprender/derivar indicadores que conformaran índices de sustentabilidad o que fueran parte de diferentes marcos de evaluación de sustentabilidad. \nEn Latinoamérica se han desarrollado sistemas para evaluar agroecosistemas con desigual grado de conceptualización y rigurosidad, y también con disímiles criterios. Dado que dichos sistemas han sido escasamente analizados tanto en su fase conceptual como en su fase aplicada, en el presente artículo nos proponemos comparar el “Marco para la Evaluación de Sistemas de Manejo de recursos naturales incorporando Indicadores de Sustentabilidad” (MESMIS) y el marco “Evaluación de Agroecosistemas Mediante Indicadores de Sustentabilidad”, buscando semejanzas y diferencias entre los mismos, en clave de resaltar sus ventajas y sus limitantes. Como conclusión general afirmamos que ninguno de los dos marcos presenta en términos globales características superadoras, no obstante el enfoque sistémico presente en el marco MESMIS le otorga mayor poder heurístico.